CLDN18.2=claudin 18 isoform. EQA=external quality assessment. G/GEJ=gastric/gastroesophageal junction. IHC=immunohistochemistry.
Hear from some of the world’s leading pathologists discussing how they test, interpret, and report CLDN18.2 expression.
Matteo Fassan, MD, PhD
Takeshi Kuwata, MD, PhD
Christoph Röcken, MD
Josef H. Rüschoff, MD
Kristina A. Matkowskyj, MD, PhD
The experts above have been contracted as paid advisors through Astellas Pharma Inc. and have received compensation for their time. The content on this website has been created by Astellas Pharma Inc. and may or may not reflect the views of the experts shown above unless explicitly specified.
Matteo Fassan is Professor of Pathology at the University of Padua (Padua, Italy) and Director of the Pathology Unit at Ca’ Foncello Hospital, part of the ULSS2 Marca Trevigiana (Treviso, Italy). His research is mainly focused on the histological and molecular characterisation of preneoplastic and neoplastic gastrointestinal pathology, with a specific interest in biomarker testing. He is also actively involved in clinical and translational research projects and has authored or coauthored more than 700 peer-reviewed publications.
Takeshi Kuwata is chief of the Department of Genetic Medicine and Services at the National Cancer Center Hospital East in Tokyo. In addition to being a board-certified pathologist, molecular pathologist, and medical geneticist, he is also an executive board member of the Japanese Gastric Cancer Association and a committee member for the Japanese classification of gastric carcinoma, the Japanese guidelines for HER2 testing in breast/gastric cancer, and the Japanese treatment guidelines for gastric cancer. Specialising in molecular and pathological diagnosis of GI tract and hereditary cancers, he is also involved in the development and standardization of new diagnostics.
Dr. Kristina Matkowskyj is a Senior Associate Consultant in the Department of Laboratory Medicine and Pathology at the Mayo Clinic in Rochester, Minnesota. She holds professional memberships with several organizations, including the United States & Canadian Academy of Pathologists, the College of American Pathologists, and the Rodger C. Haggitt Gastrointestinal Pathology Society. Dr. Matkowskyj served as a member of the NCCN Esophageal and Gastric Guideline panel and the MSI-H and Biomarker subcommittees. She is an editorial board member for Human Pathology and an ad hoc reviewer for several other peer-reviewed scientific journals.
Professor Dr. Christoph Röcken is director of the Department of Pathology at the University Hospital Schleswig-Holstein (UKSH) and was elected vice dean of the Faculty of Medicine in 2012. He was a consultant in the Department of Pathology for the Faculty of Medicine at the Otto-von-Guericke University after completing his PhD and rose to become associate professor in the specialist field of pathology at the Faculty of Medicine in 2005. From 2006 to 2009, he was university professor and vice director of the Institute of Pathology, Charité University-Hospital Berlin, and since 2009 he has been university professor and director of the Institute of Pathology, Christian-Albrechts-University Kiel. Professor Röcken is a member of the American Association for Cancer Research and the European Society of Pathology. He is also chairman of the Working Group of Pathology, the German Cancer Society, as well as a board member of the German Society of Pathology and the German Society for Amyloid Diseases. He has published 426 articles in hepato-gastrointestinal pathology and diagnostics in several peer-reviewed journals.
Professor Dr. Rüschoff is senior consultant in pathology at Discovery Life Sciences in Kassel, Germany. His prior positions include full professor at the Institute of Pathology at the University of Regensburg, director of the Institute of Pathology at Klinikum Kassel, and acting director of the Department of Gastroenteropathology at the University of Göttingen and CMO Institute of Pathology Nordhessen. He cofounded the clinical research organization Targos Molecular Pathology GmbH in 2005 and has participated in more than 300 clinical trials pertaining to breast, gastric, lung, and skin cancers. He is also extensively published, with more than 300 original articles, review articles, and book chapters.